VUF 5574

• Supplier: Tocris Bioscience
• Catalog: 5668
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 280570-45-8
• Chemical Name: N-(2-Methoxyphenyl)-N'-[2-(3-pyrindinyl)-4-quinazolinyl]-urea
• Formula: C21H17N5O2
• Molecular Weight: 371.39
• Purity: >98 %
• Description: Potent, selective, competitive antagonist for the human adenosine A 3 receptor (K i = 4 nM). Displays ≥ 2500-fold selectivity over A 1 and A 2A receptors.

Product References

New potent and selective human adenosine A(3) receptor antagonists. - New potent and selective human adenosine A(3) receptor antagonists.

Baraldi PG, Borea PA. Trends Pharmacol Sci. 2000 Dec;21(12):456-9.

Isoquinoline and quinazoline urea analogues as antagonists for the human - Isoquinoline and quinazoline urea analogues as antagonists for the human

van Muijlwijk-Koezen JE, Timmerman H, van der Goot H, Menge WM, Frijtag Von Drabbe Kunzel J, de Groote M, IJzerman AP. J Med Chem. 2000 Jun 1;43(11):2227-38.