Trametinib

Name Trametinib
Supplier Biorbyt
Catalog orb153631
Prices $264.00, $349.00, $366.00, $408.00, $502.00, $884.00, $1,369.00, $2,448.00
Sizes 10 mg, 25 mg, 100 mg, 50 mg, 200 mg, 500 mg, 1 g, 2 g
Cas Number [871700-17-3]
Pubchem 11707110
Chemical Name N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
Formula C26H23FIN5O4
Molecular Weight 615.39 g/mol
Purity >99% pure
Description Trametinib is also known as GSK-1120212, JTP-74057. Trametinib is a selective MEK inhibitor. It blocked the cell growth potently in most tumor lines with mutant BRAF or Ras. Trametinib binds to MEK 1 and 2, dual specificity threonine/tyrosine kinases often upregulated in various cancer cell types, play a key role in the activation of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth.
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