Name |
Trametinib
|
Supplier |
Biorbyt
|
Catalog |
orb153631
|
Prices |
$264.00, $349.00, $366.00, $408.00, $502.00, $884.00, $1,369.00, $2,448.00
|
Sizes |
10 mg, 25 mg, 100 mg, 50 mg, 200 mg, 500 mg, 1 g, 2 g
|
Cas Number |
[871700-17-3]
|
Pubchem |
11707110
|
Chemical Name |
N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
|
Formula |
C26H23FIN5O4
|
Molecular Weight |
615.39 g/mol
|
Purity |
>99% pure
|
Description |
Trametinib is also known as GSK-1120212, JTP-74057. Trametinib is a selective MEK inhibitor. It blocked the cell growth potently in most tumor lines with mutant BRAF or Ras. Trametinib binds to MEK 1 and 2, dual specificity threonine/tyrosine kinases often upregulated in various cancer cell types, play a key role in the activation of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth.
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