| Name | A 438079 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5781 |
| Prices | $169.00, $705.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 899431-18-6 |
| Chemical Name | 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridinehydrochloride |
| Formula | C13H9Cl2N5.HCl |
| Molecular Weight | 342.61 |
| Purity | >98 % |
| Description | Competitive P2X 7 receptor antagonist (pIC 50 = 6.9 for the inhibition of Ca 2+ influx in the human recombinant P2X 7 cell line). Devoid of activity at other P2 receptors (IC 50 >> 10 μ M). Possesses antinociceptive activity in models of neuropathic pain in vivo . Inhibits methamphetamine-induced microglial migration and phagocytosis in vitro . |
| Supplier Page | Shop |