Delavirdine mesylate

Name Delavirdine mesylate
Supplier Tocris Bioscience
Catalog 5774
Prices $209.00, $879.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 147221-93-0
Chemical Name 1-[3-[(1-Methylethyl)amino]-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]-piperazinemonomethanesulfonate
Formula C22H28N6O3S.CH3SO3H
Molecular Weight 552.67
Purity >99 %
Description Non-nucleoside reverse transcriptase inhibitor (NNRTI). Selectively inhibits HIV-1 reverse transcriptase (RNA-dependent DNA polymerase) over other cellular polymerases (IC 50 values are 0.26, 440 and >550 μ M for HIV-1 reverse transcriptase, DNA polymerase α and DNA polymerase δ ). Prevents HIV-1 spread in vivo and blocks viral replication in peripheral blood lymphocytes. Orally active.
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