des-His 1 -[Glu 9 ]-Glucagon (1-29) amide

• Supplier: Tocris Bioscience
• Catalog: 5621
• Prices: $289.00
• Sizes: 1 mg
• Function Type: Antagonist
• Cas Number: 110084-95-2
• Formula: C148H221N41O47S
• Molecular Weight: 3358.68
• Description: Glucagon receptor antagonist (pA 2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro . Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo . Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.