| Name | GNF 2 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5655 |
| Prices | $225.00, $925.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 778270-11-4 |
| Chemical Name | 3-[6-[[4-(Trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]benzamide |
| Formula | C18H13F3N4O2 |
| Molecular Weight | 374.32 |
| Purity | >98 % |
| Description | Allosteric inhibitor of Bcr-Abl tyrosine kinase activity (IC 50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr-Abl-expressing cells. Selective for Bcr-Abl over a panel of serine, threonine and tyrosine kinases. Non-ATP-competitive. |
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