IMD 0354

• Supplier: Tocris Bioscience
• Catalog: 5906
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 978-62-1
• Chemical Name: N-[3,5-Bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide
• Formula: C15H8ClF6NO2
• Molecular Weight: 383.67
• Purity: >99 %
• Description: Inhibitor of I κ B kinase- β (IKK β ) that blocks NF- κ B nuclear translocation. Attenuates myocardial ischemia/reperfusion injury by decreasing expression of adhesion molecules ICAM-1 and P-selectin and inhibiting cytokine and chemokine production in cardiomyocytes. Induces G 0 /G 1 cell cycle arrest and apoptosis in HMC-1 and breast cancer cells.