| Name | Ispinesib |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5808 |
| Prices | $245.00, $1,005.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 336113-53-2 |
| Chemical Name | N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methylbenzamide |
| Formula | C30H33ClN4O2 |
| Molecular Weight | 517.06 |
| Purity | >98 % |
| Description | High affinity allosteric kinesin spindle protein (KSP) inhibitor (K i app = 1.7 nM). Exhibits >10,000-fold selectivity for KSP over a range of other mitotic kinesins. Inhibits proliferation and induces apoptosis of prostate and breast cancer cells in vitro . Induces tumor regression of breast cancer cell xenografts in mice. |
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