JP 1302 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 5853
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 1259314-65-2
• Chemical Name: N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinaminedihydrochloride
• Formula: C24H24N4.2HCl
• Molecular Weight: 441.4
• Purity: >99 %
• Description: α 2C -adrenoceptor antagonist that displays ~ 50-fold selectivity over other α 2 -adrenoceptor subtypes (K i values are 28, 1470, 1700 and 3150 nM for human α 2C , α 2B , α 2D and α 2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35 GTP γ S binding in vitro (K B = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo .