LM 10

• Supplier: Tocris Bioscience
• Catalog: 5365
• Prices: $85.00, $359.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1316695-35-8
• Chemical Name: 6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole
• Formula: C11H8FN5
• Molecular Weight: 229.21
• Purity: >98 %
• Description: Selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC 50 values are 0.62 and 2 μ M for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.