OAC-1

Name OAC-1
Supplier Tocris Bioscience
Catalog 5664
Prices $139.00, $585.00
Sizes 10 mg, 50 mg
Function Type Activator
Cas Number 300586-90-7
Chemical Name N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
Formula C14H11N3O
Molecular Weight 237.26
Purity >98 %
Description Oct4 activator. Enhances and accelerates iPSC reprogramming in the presence of 4F (Oct4, Sox2, c-Myc and Klf4) by ~20-fold compared to 4F alone. Induces mRNA expression of Oct4, Sox2 and Nanog and also Tet1. Displays no effects on p53-p21 pathway or Wnt- β -catenin signaling.
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