8-pCPT-2-O-Me-cAMP-AM

• Supplier: Tocris Bioscience
• Catalog: 5871
• Prices: $175.00
• Sizes: 100 µg
• Function Type: Activator
• Cas Number: 1152197-23-3
• Chemical Name: 8-(4-Chlorophenylthio)-2'-O-methyladenosine-3',5'-cyclicmonophosphateacetoxymethylester
• Formula: C20H21ClN5O8PS
• Molecular Weight: 557.9
• Purity: >97 %
• Description: Selective Epac activator; cAMP analog. Induces Rap activation and junction tightening in HUVECs; triggers adhesion of Jurkat-Epac1 cells to fibronectin. Stimulates insulin secretion in rat INS-1 cells. More potent, cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645). This product is a mixture of axial and equatorial isomers. Both isomers give 8CPT-2Me-cAMP after esterase cleavage.