PF 573228

Name PF 573228
Supplier Tocris Bioscience
Catalog 5754
Prices $199.00, $825.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 869288-64-2
Chemical Name 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
Formula C22H20F3N5O3S
Molecular Weight 491.49
Purity >98 %
Description Potent and selective inhibitor of focal adhesion kinase (FAK) (IC 50 = 4 nM). Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro .
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