| Name | PF 670462 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5939 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 950912-80-8 |
| Chemical Name | 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride |
| Formula | C19H20FN5.2HCl |
| Molecular Weight | 410.32 |
| Purity | >99 % |
| Description | Potent and selective casein kinase 1 ε (CK1 ε ) and CK1 δ inhibitor (IC 50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation (EC 50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo . |
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