Tiplaxtinin

Name Tiplaxtinin
Supplier Tocris Bioscience
Catalog 5902
Prices $119.00, $505.00
Sizes 10 mg, 50 mg
Function Type Activator
Cas Number 393105-53-8
Chemical Name α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-aceticacid
Formula C24H16F3NO4
Molecular Weight 439.38
Purity >98 %
Description Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC 50 = 2.7 μ M). Induces vascular smooth muscle cell apoptosis in vitro and reduces carotid artery neointimal formation in a rat vascular injury model. Promotes thrombolysis in rat and dog models of acute arterial thrombosis. Orally available.
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