Name | Tiplaxtinin |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5902 |
Prices | $119.00, $505.00 |
Sizes | 10 mg, 50 mg |
Function Type | Activator |
Cas Number | 393105-53-8 |
Chemical Name | α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-aceticacid |
Formula | C24H16F3NO4 |
Molecular Weight | 439.38 |
Purity | >98 % |
Description | Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC 50 = 2.7 μ M). Induces vascular smooth muscle cell apoptosis in vitro and reduces carotid artery neointimal formation in a rat vascular injury model. Promotes thrombolysis in rat and dog models of acute arterial thrombosis. Orally available. |
Supplier Page | Shop |