Brefeldin A

Name Brefeldin A
Supplier BioGems
Catalog 2031560
Prices $40.00, $105.00
Sizes 5 mg, 25 mg
Function Type Inhibitor
Cas Number 20350-15-6
Chemical Name (1S,2E,7S,10E,12R,13R,15S)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one
Formula C16H24O4
Molecular Weight 280.4
Purity ≥98%
Description Brefeldin A is a lactone antibiotic originating discovered in fungi capable of inhibiting protein transport from the endolasmic reticulum to the Golgi apparatus. It is reported to act on the guanine nucleotide exchange factor named GBF1 that mediates the formation of transport vesicles and the unfolded protein response can result in apoptosis in some cells.
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