CH 223191

Name CH 223191
Supplier BioGems
Catalog 3012272
Prices $145.00, $600.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 301326-22-7
Chemical Name 2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
Formula C19H19N5O
Molecular Weight 333.4
Purity ≥95%
Description CH 223191 is a specific and potent antagonist to the aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor that is involved in drug and xenobiotic metabolism. Unlike other AhR antagonists, it does not react with the estrogen receptor and is observed to effect AhR-dependent reporter gene expression in human, mouse, rat, and guinea pig cell lines. CH223191 is reported to exhibit AHR-independent pro-proliferative properties.
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