DAPT

Name DAPT
Supplier BioGems
Catalog 2088055
Prices $150.00, $620.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 208255-80-5
Chemical Name tert-butyl(2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
Formula C23H26F2N2O4
Molecular Weight 432.5
Purity ≥95%
Description DAPT is a potent inhibitor of the gamma-secretase complex, which is an internal protease that cleaves single-pass transmembrane proteins at residues within the transmembrane domain. DAPT also indirectly inhibits the Notch protein. It is reported promote neuronal differentiation and enhance the apoptosis of human tongue carcinoma cells.
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