| Name | Rapamycin |
|---|---|
| Supplier | BioGems |
| Catalog | 5318893 |
| Prices | $35.00, $125.00 |
| Sizes | 1 mg, 10 mg |
| Function Type | Inhibitor |
| Cas Number | 53123-88-9 |
| Chemical Name | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine1,5,11,28,29(4H,6H,31H)-pentone |
| Formula | C51H79NO13 |
| Molecular Weight | 914.2 |
| Purity | ≥95% |
| Description | Rapamycin was first evaluated as an antifungal agent, but is now studied for its potent immunosuppressive and antiproliferative properties. It forms a complex with FKBP12 and directly binds to mTORC1, inhibiting the functions of the mTOR pathway. Rapamycin is reported to block protein synthesis, arrest cell cycle progression, and inhibit IL-2 signal transduction mechanisms. |
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