RG108

• Supplier: BioGems
• Catalog: 4822608
• Prices: $105.00, $435.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 48208-26-0
• Chemical Name: (2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoicacid
• Formula: C19H14N2O4
• Molecular Weight: 334.3
• Purity: ≥98%
• Description: RG108 is a non-nucleoside DNA methyltransferase inhibitor by binding and blocking the active site of the methyltransferase enzyme. Unlike nucleoside based inhibitors, it reduces the methylation of DNA without detectable toxicity. RG108 is reported to be used to reactivate epigenetically silenced tumor suppressor genes and enhance the reprogramming efficiency of induced pluripotent stem cells.