| Name | SB 525334 |
|---|---|
| Supplier | BioGems |
| Catalog | 3562015 |
| Prices | $125.00, $485.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 356559-20-1 |
| Chemical Name | 6-[2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline |
| Formula | C21H21N5 |
| Molecular Weight | 343.4 |
| Purity | ≥98% |
| Description | SB 525334 is a selective and potent inhibitor of the TGF-Beta receptor 1 (ALK5). It exhibits no inhibition of ALK2, ALK3, and ALK6. It blocks the activation of Smad2/3 by TGF-β1 in renal proximal tubule cells and attenuates bleomycin-induced pulmonary fibrosis. |
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