| Description |
Valproic Acid (VPA) is a histone deacetylase (HDAC) inhibitor with anti-inflammatory, neuroprotective and anticonvulsant properties. It also inhibits the enzymes in gamma-Aminobutyric acid (GABA) metabolism leading to increased levels of GABA and also, to deplete cellular inositol synthesis. VPA is reported to promote the self-renewal and differentiation of hematopoietic progenitor cells and be useful in generating induced pluripotent stem cells, in combination with other small molecules and growth factors.
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