XAV939

• Supplier: BioGems
• Catalog: 2848932
• Prices: $90.00, $195.00
• Sizes: 10 mg, 25 mg
• Function Type: Inhibitor
• Cas Number: 284028-89-3
• Chemical Name: 2-[4-(trifluoromethyl)phenyl]-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one
• Formula: C14H11F3N2OS
• Molecular Weight: 312.3
• Purity: ≥98%
• Description: XAV939 is a potent inhibitor of TNKS 1 and 2, which promotes the degradation of Beta-catenin and increases the protein levels of the axin-GSK3Beta complex. It is reported to promote cardiomyogenic development in progenitor cells, inhibits the proliferation of certain carcinoma cell lines, and enhances the induction of cortical interneurons from embryonic stem cells.