| Name | BMS 299897 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5654 |
| Prices | $205.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 290315-45-6 |
| Chemical Name | 2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoicacid |
| Formula | C24H21ClF3NO4S |
| Molecular Weight | 511.94 |
| Purity | >98 % |
| Description | Orally active, potent γ -secretase inhibitor (IC 50 = 12 nM). Inhibits A β 40 and A β 42 formation in vitro (IC 50 values are 7.4 and 7.9 nM respectively) and reduces A β in the brain, plasma and cerebrospinal fluid in vivo . Exhibits no Notch toxicity. Brain penetrant. |
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