| Name | Ciliobrevin A |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5870 |
| Prices | $175.00, $709.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 302803-72-1 |
| Chemical Name | 2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile |
| Formula | C17H9Cl2N3O2 |
| Molecular Weight | 358.18 |
| Purity | >98 % |
| Description | Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC 50 = 7 μ M) downstream of Smo. Perturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity. |
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