(±)-HIP-A

• Supplier: Tocris Bioscience
• Catalog: 5961
• Prices: $189.00
• Sizes: 10 mg
• Function Type: Blocker
• Cas Number: 227619-64-9
• Chemical Name: (±)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylicacid
• Formula: C6H8N2O4
• Molecular Weight: 172.14
• Purity: >98 %
• Description: Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [ 3 H]D-aspartate release (IC 50 = 1.6 μ M) rather than [ 3 H]L-glutamate uptake (IC 50 = 18 μ M). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC 50 values are 43 and 8 μ M respectively). .