| Name | INCB 3284 dimesylate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 6007 |
| Prices | $225.00, $925.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 887401-93-6 |
| Chemical Name | N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamidedimethanesulfonate |
| Formula | C26H31F3N4O4.2CH4O3S |
| Molecular Weight | 712.76 |
| Purity | >98 % |
| Description | Potent, selective hCCR2 antagonist. Exhibits potent antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity (IC 50 values are 3.7 and 4.7 nM respectively). Also displays weak hERG activity; inhibits the hERG potassium current (IC 50 = 84 μ M). Orally bioavailable. |
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