JZP 361

• Supplier: Tocris Bioscience
• Catalog: 4715
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1680193-80-9
• Chemical Name: [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-triazol-1-yl)methanone
• Formula: C22H20ClN5O
• Molecular Weight: 405.88
• Purity: >99 %
• Description: Potent and selective reversible MAGL inhibitor (IC 50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC 50 values are 1.79 and 7.24 μ M, respectively). Displays affinity for H 1 receptors (pA 2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μ M.