LM 22A4

Name LM 22A4
Supplier Tocris Bioscience
Catalog 5794
Prices $179.00, $745.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 37988-18-4
Chemical Name N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Formula C15H21N3O6
Molecular Weight 339.34
Purity >98 %
Description Potent tropomyosin-related kinase B (TrkB) agonist (IC 50 = 47 nM). Induces activation of Trk, Akt and ERK in mouse hippocampus and striatum. Reverses deficits in motor task learning in mice following traumatic brain injury; restores respiratory function in a rat model of Rett syndrome.
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