Montelukast sodium

Name Montelukast sodium
Supplier Tocris Bioscience
Catalog 5770
Prices $75.00, $315.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 151767-02-1
Chemical Name 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneaceticacidsodiumsalt
Formula C35H35ClNNaO3S
Molecular Weight 608.17
Purity >99 %
Description Cysteinyl leukotriene receptor 1 (CysLT 1 ) and GPR17 antagonist. Blocks pentylenetetrazole -induced seizures, blood brain barrier (BBB) disruption and leukocyte migration in mice. Reduces neuroinflammation, improves BBB integrity, enhances learning and memory, and restores hippocampal neurogenesis and cognitive function in aged rats. Orally active and brain penetrant.
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