Name | Perifosine |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5166 |
Prices | $95.00, $399.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 157716-52-4 |
Chemical Name | Octadecyl-(1,1-dimethyl-4-piperidylio)phosphate |
Formula | C25H52NO4P |
Molecular Weight | 461.66 |
Purity | >99 % |
Description | PKB/Akt inhibitor; accumulates in and reorganizes lipid rafts disrupting Akt signaling. Also inhibits MAPK pathway and induces autophagy. Induces apoptosis in leukemia cell lines. Decreases K v 2.1 current amplitude by modulating its inactivation gating. Antitumor. Orally bioavailable. |
Supplier Page | Shop |