Rose Bengal

Name Rose Bengal
Supplier Tocris Bioscience
Catalog 1332
Prices $45.00
Sizes 50 mg
Function Type Inhibitor
Cas Number 632-69-9
Chemical Name 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-onedisodiumsalt
Formula C20H2Cl4I4Na2O5
Molecular Weight 1017.64
Purity >98 %
Description Potent VGlut and vesicular monoamine transporter (VMAT) inhibitor (K i values are 19 and 64 nM, respectively). Inhibits ATP dependent vesicular glutamate uptake (IC 50 = 37 nM) and diminishes the amount of exocytotically released glutamate in synaptosomes. Decreases synaptic transmission in the dentate gyrus. Also stains exposed epithelium in the eye. Cell permeable.
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