Name | Rose Bengal |
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Supplier | Tocris Bioscience |
Catalog | 1332 |
Prices | $45.00 |
Sizes | 50 mg |
Function Type | Inhibitor |
Cas Number | 632-69-9 |
Chemical Name | 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-onedisodiumsalt |
Formula | C20H2Cl4I4Na2O5 |
Molecular Weight | 1017.64 |
Purity | >98 % |
Description | Potent VGlut and vesicular monoamine transporter (VMAT) inhibitor (K i values are 19 and 64 nM, respectively). Inhibits ATP dependent vesicular glutamate uptake (IC 50 = 37 nM) and diminishes the amount of exocytotically released glutamate in synaptosomes. Decreases synaptic transmission in the dentate gyrus. Also stains exposed epithelium in the eye. Cell permeable. |
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