| Name | SKF 83566 hydrobromide |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5719 |
| Prices | $99.00, $419.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 108179-91-5 |
| Chemical Name | 8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-olhydrobromide |
| Formula | C17H18BrNO.HBr |
| Molecular Weight | 413.15 |
| Purity | >98 % |
| Description | Potent and selective D 1 -like dopamine receptor antagonist (K i ~ 0.56 nM for D 1 ; K B = 2 μ M for D 2 ). Also antagonist at the vascular 5-HT 2 receptor (K i = 11 nM). Displays selective inhibition of adenylyl cyclase 2 (AC2); inactive against AC1 or AC5. Centrally active following systemic administration in vivo . |
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