| Name | SR 1001 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5868 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 1335106-03-0 |
| Chemical Name | N-[4-Methyl-5-[[[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]sulfonyl]-2-thiazolylacetamide |
| Formula | C15H13F6N3O4S2 |
| Molecular Weight | 477.4 |
| Purity | >98 % |
| Description | Retinoic acid receptor-related orphan receptor (ROR) α and γ inverse agonist (K i values are 172 and 111 nM for ROR α and ROR γ respectively). Demonstrates no activity at ROR β or LXR. Suppresses T h 17 cell differentiation and cytokine expression and reduces the severity of disease in an animal model of mulitple sclerosis. |
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