Name | SR 9238 |
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Supplier | Tocris Bioscience |
Catalog | 5855 |
Prices | $149.00, $629.00 |
Sizes | 10 mg, 50 mg |
Function Type | Agonist |
Cas Number | 1416153-62-2 |
Chemical Name | Ethyl5-[[[[3'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate |
Formula | C31H33NO7S2 |
Molecular Weight | 595.73 |
Purity | >98 % |
Description | Potent and selective LXR inverse agonist (IC 50 values are 43 and 214 nM for LXR β and LXR α , respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hepatic steatosis in obese mice. |
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