| Name | TQS |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5918 |
| Prices | $175.00, $709.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 353483-92-8 |
| Chemical Name | 3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide |
| Formula | C22H20N2O2S |
| Molecular Weight | 376.47 |
| Purity | >98 % |
| Description | Type II positive allosteric modulator of α 7 nACh receptors (pEC 50 = 5.5). Displays no agonist activity at α 7 receptors at concentrations up to 0.1 mM; potentiates agonist-evoked responses and reduces rate of desensitization of α 7 nAChRs. Exhibits potency and efficacy similar to PNU 120596 (Cat. No. 2498). |
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