| Name | VU 0422288 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5693 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 1630936-95-6 |
| Chemical Name | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Formula | C17H11Cl2N3O2 |
| Molecular Weight | 360.19 |
| Purity | >98 % |
| Description | Group III mGlu receptor positive allosteric modulator (EC 50 values are 108, 125 and 146 nM for mGlu 4 , mGlu 8 and mGlu 7 respectively). Exhibits selectivity over a panel of 68 other GPCRs, ion channels and transporters. Potentiates mGlu 7 -mediated reductions in excitatory post synaptic potentials in hippocampal slices. |
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