Name | ACET |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5879 |
Prices | $349.00 |
Sizes | 10 mg |
Function Type | Antagonist |
Cas Number | 936095-50-0 |
Chemical Name | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione |
Formula | C20H19N3O6S |
Molecular Weight | 429.45 |
Purity | >98 % |
Description | Potent and selective GluR5-containing kainate receptor antagonist (IC 50 = 7 nM) that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations. |
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