ACET

Name ACET
Supplier Tocris Bioscience
Catalog 5879
Prices $349.00
Sizes 10 mg
Function Type Antagonist
Cas Number 936095-50-0
Chemical Name (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione
Formula C20H19N3O6S
Molecular Weight 429.45
Purity >98 %
Description Potent and selective GluR5-containing kainate receptor antagonist (IC 50 = 7 nM) that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.
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