AM 580

Name AM 580
Supplier Tocris Bioscience
Catalog 5789
Prices $155.00, $645.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 102121-60-8
Chemical Name 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoicacid
Formula C22H25NO3
Molecular Weight 351.44
Purity >98 %
Description An analog of retinoic acid that acts as a selective RAR α agonist (EC 50 values are 0.3, 8.6 and 13 nM for RAR α , RAR β and RAR γ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFN γ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro .
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