Name | AM 580 |
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Supplier | Tocris Bioscience |
Catalog | 5789 |
Prices | $155.00, $645.00 |
Sizes | 10 mg, 50 mg |
Function Type | Agonist |
Cas Number | 102121-60-8 |
Chemical Name | 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoicacid |
Formula | C22H25NO3 |
Molecular Weight | 351.44 |
Purity | >98 % |
Description | An analog of retinoic acid that acts as a selective RAR α agonist (EC 50 values are 0.3, 8.6 and 13 nM for RAR α , RAR β and RAR γ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFN γ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro . |
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