AZ 10417808

• Supplier: Tocris Bioscience
• Catalog: 5872
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 331645-84-2
• Chemical Name: 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide
• Formula: C18H13Cl2N5O4
• Molecular Weight: 434.23
• Purity: >98 %
• Description: Selective non-peptide inhibitor of caspase-3 (K i = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (K i > 10 μ M). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC 50 = 14.9 μ M).