5-Azacytidine

Name 5-Azacytidine
Supplier Tocris Bioscience
Catalog 5742
Prices $59.00
Sizes 50 mg
Function Type Inhibitor
Cas Number 320-67-2
Chemical Name 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Formula C8H12N4O5
Molecular Weight 244.2
Purity >98 %
Description DNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells; induces differentiation of mesenchymal stem cells into cardiomyocytes.
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