Azidothymidine

• Supplier: Tocris Bioscience
• Catalog: 5765
• Prices: $59.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 30516-87-1
• Chemical Name: 3'-Azido-3'-deoxythymidine
• Formula: C10H13N5O4
• Molecular Weight: 267.24
• Purity: >99 %
• Description: Selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α . Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice. Orally bioavailable and brain penetrant. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.