BMS CCR2 22

Name BMS CCR2 22
Supplier Tocris Bioscience
Catalog 5983
Prices $119.00, $255.00, $1,045.00
Sizes 1 mg, 10 mg, 50 mg
Function Type Antagonist
Cas Number 445479-97-0
Chemical Name 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
Formula C28H34F3N5O4S
Molecular Weight 593.66
Purity >98 %
Description High affinity CCR2 chemokine receptor antagonist (IC 50 = 5.1 nM). Displays potent functional antagonism, IC 50 values are 1 and 18 nM for chemotaxis and antagonism of calcium flux respectively. Selective over CCR3.
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