Cilastatin sodium

Name Cilastatin sodium
Supplier Tocris Bioscience
Catalog 6210
Prices $109.00, $455.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 81129-83-1
Chemical Name (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicacidsodiumsalt
Formula C16H25N2NaO5S
Molecular Weight 380.43
Purity >99 %
Description Dipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a K i value of 0.11 μ M. Inhibits metabolism of LTD 4 to LTE 4 and the hydrolysis of β -lactam antibiotics. Nephroprotective; reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells.
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