Name | Cilastatin sodium |
---|---|
Supplier | Tocris Bioscience |
Catalog | 6210 |
Prices | $109.00, $455.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 81129-83-1 |
Chemical Name | (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicacidsodiumsalt |
Formula | C16H25N2NaO5S |
Molecular Weight | 380.43 |
Purity | >99 % |
Description | Dipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a K i value of 0.11 μ M. Inhibits metabolism of LTD 4 to LTE 4 and the hydrolysis of β -lactam antibiotics. Nephroprotective; reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. |
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