Name | CZC 54252 hydrochloride |
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Supplier | Tocris Bioscience |
Catalog | 6071 |
Prices | $209.00, $879.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 1191911-27-9 |
Chemical Name | N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamidehydrochloride |
Formula | C22H25ClN6O4S.HCl |
Molecular Weight | 541.45 |
Purity | >98 % |
Description | Potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC 50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). Attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC 50 = 1 nM). |
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