CZC 54252 hydrochloride

Name CZC 54252 hydrochloride
Supplier Tocris Bioscience
Catalog 6071
Prices $209.00, $879.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1191911-27-9
Chemical Name N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamidehydrochloride
Formula C22H25ClN6O4S.HCl
Molecular Weight 541.45
Purity >98 %
Description Potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC 50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). Attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC 50 = 1 nM).
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