| Name | EX 527 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5833 |
| Prices | $89.00, $189.00, $765.00 |
| Sizes | 1 mg, 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 49843-98-3 |
| Chemical Name | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Formula | C13H13ClN2O |
| Molecular Weight | 248.71 |
| Purity | >98 % |
| Description | Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC 50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents. |
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