5-Fluorouracil

Name 5-Fluorouracil
Supplier Tocris Bioscience
Catalog 5501
Prices $59.00
Sizes 50 mg
Cas Number 51-21-8
Chemical Name 5-Fluoro-2,4-(1H,3H)-pyrimidinedione
Formula C4H3FN2O2
Molecular Weight 130.08
Purity >99 %
Description Anticancer agent. Metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.
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