GSK 137647

• Supplier: Tocris Bioscience
• Catalog: 6056
• Prices: $99.00, $419.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 349085-82-1
• Chemical Name: 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
• Formula: C16H19NO3S
• Molecular Weight: 305.39
• Purity: >99 %
• Description: Potent and selective FFA4 (GPR120) agonist (pEC 50 values are 6.3, 6.2 and 6.1 at the human, mouse and rat receptor, respectively). Exhibits ≥100-fold selectivity against a panel of 61 targets including FFA1, FFA2 and FFA3. Enhances glucose-stimulated insulin secretion in MIN6 cells. Induces intracellular calcium accumulation in U2OS cells; this activity is inhibited by AH 7614 (Cat. No. 5256).