2 R ,6 R -Hydroxynorketamine hydrochloride

Name 2 R ,6 R -Hydroxynorketamine hydrochloride
Supplier Tocris Bioscience
Catalog 6124
Prices $269.00
Sizes 10 mg
Cas Number 1430202-69-9
Chemical Name (2R,6R)-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanonehydrochloride
Formula C12H14ClNO2.HCl
Molecular Weight 276.16
Purity >98 %
Description Ketamine metabolite. Enhances AMPA receptor-mediated excitatory post-synaptic potentials in the CA1 region of hippocampal slices. Decreases intracellular D -serine (a NMDA co-agonist) concentrations in PC-12 cells (IC 50 = 0.68 nM). Exerts antidepressant effects in mice. Lacks ketamine-related side effects.
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