Itraconazole

• Supplier: Tocris Bioscience
• Catalog: 5692
• Prices: $59.00
• Sizes: 50 mg
• Function Type: Antagonist
• Cas Number: 84625-61-6
• Chemical Name: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
• Formula: C35H38Cl2N8O4
• Molecular Weight: 705.63
• Purity: >99 %
• Description: SMO antagonist (IC 50 = 690 nM); acts at different binding site to cyclopamine (Cat. No. 1623). Also cytochrome p450 inhibitor (IC 50 = 16-26 nM). Inhibits cell cycle at G 1 phase in vitro and blocks angiogenesis in vivo (IC 50 = 160 nM). Antifungal.